(19)
(11) EP 0 528 975 A1

(12)

(43) Date of publication:
03.03.1993 Bulletin 1993/09

(21) Application number: 91910609.0

(22) Date of filing: 06.05.1991
(51) International Patent Classification (IPC): 
A61K 31/ 04( . )
A61K 31/ 085( . )
A61K 31/ 135( . )
A61K 31/ 235( . )
A61K 31/ 34( . )
A61K 31/ 395( . )
A61P 15/ 00( . )
C07D 307/ 83( . )
C07D 405/ 14( . )
A61K 31/ 05( . )
A61K 31/ 12( . )
A61K 31/ 215( . )
A61K 31/ 275( . )
A61K 31/ 343( . )
A61P 13/ 02( . )
A61P 35/ 00( . )
C07D 405/ 10( . )
(86) International application number:
PCT/US1991/003130
(87) International publication number:
WO 1991/017749 (28.11.1991 Gazette 1991/27)
(84) Designated Contracting States:
AT BE CH DE DK ES FR GB IT LI LU NL SE

(30) Priority: 17.05.1990 US 19900525270

(71) Applicant: BAYLOR COLLEGE OF MEDICINE
Houston, TX 77030 (US)

(72) Inventors:
  • MARKAVERICH, Barry
    The Woodlands, TX 77381 (US)
  • GREGORY, Rebecca
    Houston, TX 77035 (US)
  • VARMA, Rajender Singh
    The Woodlands, TX 77381 (US)
  • VARMA, Manju
    The Woodlands, TX 77381 (US)
  • CLARK, James
    Houston, TX 77074 (US)
  • WALDREP, John C.
    The Woodlands, TX 77381 (US)

(74) Representative: Adams, William Gordon, et al 
RAWORTH, MOSS & COOK 36 Sydenham Road
Croydon Surrey CR0 2EF
Croydon Surrey CR0 2EF (GB)

   


(54) GROWTH INHIBITORS AND METHODS OF TREATING CANCER AND CELL PROLIFERATIVE DISEASES