(19)

(11)

EP 0 530 242 A1

(12)

(43) Date of publication: 10.03.1993 Bulletin 1993/10 (21) Application number: 91909433.0 (22) Date of filing: 20.05.1991

(51) International Patent Classification (IPC):  A61K 31/ 785( . ) C08F 8/ 32( . ) A61P 3/ 06( . ) C08F 8/ 44( . ) (86) International application number: PCT/GB1991/000788 (87) International publication number: WO 1991/018027 (28.11.1991 Gazette 1991/27)

(84) Designated Contracting States: CH DE FR GB IT LI NL (30) Priority: 21.05.1990 GB 19900011332 (71) Applicant: SMITH KLINE & FRENCH LABORATORIES LIMITED Welwyn Garden City Hertfordshire, AL7 1EY (GB)	(72) Inventors: BENSON, G. M. SmithKline Beecham Pharmac. Hertfordshire AL6 9AR e AL6 9AR (GB) HICKEY, D. M. B. SmithKline Beecham Pharmac. HertfordshireAL6 9AR ertfordshire (GB) (74) Representative: Giddings, Peter John, Dr., et al  SmithKline Beecham plc Corporate Intellectual Property SB House Great West Road Brentford, Middlesex TW8 9BD Brentford, Middlesex TW8 9BD (GB)