(19)

(11)

EP 0 531 337 A1

(12)

(43) Date of publication: 17.03.1993 Bulletin 1993/11 (21) Application number: 91909445.0 (22) Date of filing: 22.04.1991

(51) International Patent Classification (IPC):  A61K( . ) A61K 8/ 37( . ) A61K 8/ 58( . ) A61Q 15/ 00( . ) A61K 8/ 26( . ) A61K 8/ 39( . ) A61K 8/ 891( . ) (86) International application number: PCT/US1991/002687 (87) International publication number: WO 1991/018587 (12.12.1991 Gazette 1991/28)

(84) Designated Contracting States: AT BE CH DE DK ES FR GB GR IT LI LU NL SE (30) Priority: 30.05.1990 US 19900530671 (71) Applicant: THE PROCTER & GAMBLE COMPANY Cincinnati, Ohio 45202 (US)	(72) Inventors: CEDENO, Alejandro Cincinnati, OH 45208 (US) LISTRO, Joseph, Anthony Maineville, OH 45039 (US) (74) Representative: Brooks, Maxim Courtney, et al  Procter & Gamble Limited Whitley Road Longbenton Newcastle-upon-Tyne NE12 9TS Newcastle-upon-Tyne NE12 9TS (GB)