(19)
(11)
EP 0 531 452 A1
(12)
(43)
Date of publication:
17.03.1993
Bulletin 1993/11
(21)
Application number:
91912531.0
(22)
Date of filing:
29.05.1991
(51)
International Patent Classification (IPC):
A61K
31/
715
( . )
C07F
9/
10
( . )
C07F
9/
6533
( . )
C07H
19/
207
( . )
A61P
31/
12
( . )
C07F
9/
40
( . )
C07H
19/
10
( . )
(86)
International application number:
PCT/US1991/003736
(87)
International publication number:
WO 1991/018914
(
12.12.1991
Gazette 1991/28)
(84)
Designated Contracting States:
AT BE CH DE DK ES FR GB GR IT LI LU NL SE
(30)
Priority:
29.05.1990
US 19900530556
(71)
Applicant:
VICAL, INC.
San Diego California 92121 (US)
(72)
Inventors:
VEN DEN BOSCH, Henk
NL-Maarn (NL)
VAN WIJK, Bert
NL-3508 TB Utrecht (NL)
KUMAR, Raj
San Diego, CA 92129 (US)
HOSTETLER, Karl, Y.
Del Mar, CA 92014 (US)
(74)
Representative:
VOSSIUS & PARTNER
Postfach 86 07 67
D-81634 München
D-81634 München (DE)
(54)
SYNTHESIS OF GLYCEROL DI- AND TRIPHOSPHATE DERIVATIVES