(19)
(11) EP 0 531 452 A1

(12)

(43) Date of publication:
17.03.1993 Bulletin 1993/11

(21) Application number: 91912531.0

(22) Date of filing: 29.05.1991
(51) International Patent Classification (IPC): 
A61K 31/ 715( . )
C07F 9/ 10( . )
C07F 9/ 6533( . )
C07H 19/ 207( . )
A61P 31/ 12( . )
C07F 9/ 40( . )
C07H 19/ 10( . )
(86) International application number:
PCT/US1991/003736
(87) International publication number:
WO 1991/018914 (12.12.1991 Gazette 1991/28)
(84) Designated Contracting States:
AT BE CH DE DK ES FR GB GR IT LI LU NL SE

(30) Priority: 29.05.1990 US 19900530556

(71) Applicant: VICAL, INC.
San Diego California 92121 (US)

(72) Inventors:
  • VEN DEN BOSCH, Henk
    NL-Maarn (NL)
  • VAN WIJK, Bert
    NL-3508 TB Utrecht (NL)
  • KUMAR, Raj
    San Diego, CA 92129 (US)
  • HOSTETLER, Karl, Y.
    Del Mar, CA 92014 (US)

(74) Representative: VOSSIUS & PARTNER 
Postfach 86 07 67
D-81634 München
D-81634 München (DE)

   


(54) SYNTHESIS OF GLYCEROL DI- AND TRIPHOSPHATE DERIVATIVES