(19)

(11)

EP 0 533 774 A1

(12)

(43) Date of publication: 31.03.1993 Bulletin 1993/13 (21) Application number: 91911145.0 (22) Date of filing: 12.06.1991

(51) International Patent Classification (IPC):  A01N 25/ 22( . ) A01N 25/ 28( . ) A01N 53/ 02( . ) A01N 53/ 08( . ) A01N 25/ 26( . ) A01N 53/ 00( . ) A01N 53/ 04( . ) B01J 13/ 02( . ) (86) International application number: PCT/GB1991/000944 (87) International publication number: WO 1991/019417 (26.12.1991 Gazette 1991/29)

(84) Designated Contracting States: AT BE CH DE DK ES FR GB GR IT LI LU NL SE (30) Priority: 13.06.1990 GB 19900013220 (71) Applicant: THE WELLCOME FOUNDATION LIMITED London NW1 2BP (GB)	(72) Inventors: MOONEY, Mary Berkhamsted, Hertfordshire HP4 2DY (GB) HORDLE, Alan Berkhamsted, Hertfordshire HP4 2DY (GB) CAYLEY, George Raymond Berkhamsted, Hertfordshire HP4 2DY (GB) (74) Representative: Vieillefosse, Jean-Claude  Département des Brevets ROUSSEL-UCLAF 111 Route de Noisy B.P. 9 F-93230 Romainville F-93230 Romainville (FR)