(19)
(11) EP 0 535 084 A1

(12)

(43) Date of publication:
07.04.1993 Bulletin 1993/14

(21) Application number: 91911687.0

(22) Date of filing: 07.06.1991
(51) International Patent Classification (IPC): 
A61K 39/ 395( . )
C07K 16/ 28( . )
C12P 21/ 08( . )
C12R 1/ 91( . )
C07K 16/ 00( . )
C12N 15/ 02( . )
A61K 38/ 00( . )
(86) International application number:
PCT/US1991/003903
(87) International publication number:
WO 1992/000100 (09.01.1992 Gazette 1992/02)
(84) Designated Contracting States:
DE FR IT

(30) Priority: 22.06.1990 US 19900542350

(71) Applicant: E.I. DU PONT DE NEMOURS AND COMPANY
Wilmington Delaware 19898 (US)

(72) Inventor:
  • GORZYNSKI, Timothy, James
    Newark, DE 19711 (US)

(74) Representative: von Kreisler, Alek, Dipl.-Chem. 
Patentanwälte von Kreisler-Selting-Werner Postfach 10 22 41
D-50462 Köln
D-50462 Köln (DE)

   


(54) IMPROVED ASCITES PRODUCTION OF MONOCLONAL ANTIBODIES USING AN IMMUNOSUPPRESSIVE ANTI-CD4-RELATED ANTIBODY