EXPRESSION VECTORS CONTAINING THE HIV $i(nef) GENE TO ENHANCE REPLICATION EFFICIENCY

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EP 0 535 161 A1

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(43)	Date of publication:
	07.04.1993 Bulletin 1993/14

(21)	Application number: 91914700.0

(22)	Date of filing: 18.06.1991

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International Patent Classification (IPC):

C12N 5/ 10^{( . )}
C12N 15/ 09^{( . )}
C12Q 1/ 68^{( . )}
G01N 33/ 569^{( . )}

C07K 14/ 16^{( . )}
C12P 21/ 00^{( . )}
G01N 33/ 53^{( . )}
C12R 1/ 91^{( . )}

(86)	International application number:
	PCT/US1991/004333

(87)	International publication number:
	WO 1991/019817 (26.12.1991 Gazette 1991/29)

(84)	Designated Contracting States:
	AT BE CH DE DK ES FR GB GR IT LI LU NL SE

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Priority:

20.06.1990 US 19900540745

(71)	Applicant: DANA FARBER CANCER INSTITUTE
	Boston Massachusetts 02115 (US)

(72)	Inventors:
	HASELTINE, William, A. Cambridge, MA 02140 (US) TERWILLIGER, Ernest Boston, MA 02215 (US) LANGHOF, Erik Watertown, MA 02172 (US)

(74)	Representative: Davies, Jonathan Mark
	Reddie & Grose 16 Theobalds Road London WC1X 8PL London WC1X 8PL (GB)

(54)	EXPRESSION VECTORS CONTAINING THE HIV $i(nef) GENE TO ENHANCE REPLICATION EFFICIENCY