(19)
(11) EP 0 536 234 A1

(12)

(43) Date of publication:
14.04.1993 Bulletin 1993/15

(21) Application number: 91912130.0

(22) Date of filing: 18.06.1991
(51) International Patent Classification (IPC): 
C12N 5/ 10( . )
A61P 31/ 12( . )
C12N 7/ 00( . )
C12N 15/ 867( . )
A61K 39/ 00( . )
A61K 48/ 00( . )
C07K 14/ 16( . )
C12N 15/ 09( . )
A61K 38/ 00( . )
C12R 1/ 91( . )
(86) International application number:
PCT/US1991/004335
(87) International publication number:
WO 1991/019798 (26.12.1991 Gazette 1991/29)
(84) Designated Contracting States:
AT BE CH DE DK ES FR GB GR IT LI LU NL SE

(30) Priority: 20.06.1990 US 19900540746

(71) Applicant: DANA FARBER CANCER INSTITUTE
Boston Massachusetts 02115 (US)

(72) Inventors:
  • SODROSKI, Joseph, G.
    Medford, MA 02155 (US)
  • HASELTINE, William, A.
    Cambridge, MA 02140 (US)
  • POZNANSKY, Mark
    Cambridge, MA 02139 (US)
  • LEVER, Andrew
    Middlexex HA5 2BX (GB)

(74) Representative: Davies, Jonathan Mark 
Reddie & Grose 16 Theobalds Road
London WC1X 8PL
London WC1X 8PL (GB)

   


(54) VECTORS CONTAINING HIV PACKAGING SEQUENCES, PACKAGING DEFECTIVE HIV VECTORS, AND USES THEREOF