(19)
(11) EP 0 540 612 A1

(12)

(43) Date of publication:
12.05.1993 Bulletin 1993/19

(21) Application number: 91913626.0

(22) Date of filing: 16.07.1991
(51) International Patent Classification (IPC): 
A61K 38/ 00( . )
A61K 38/ 36( . )
A61K 47/ 48( . )
C07C 43/ 178( . )
C07C 205/ 14( . )
C07C 233/ 18( . )
C07C 271/ 16( . )
C07D 209/ 48( . )
C07K 16/ 00( . )
C07K 16/ 44( . )
C07K 19/ 00( . )
G01N 33/ 547( . )
A61K 38/ 22( . )
A61K 39/ 395( . )
A61K 49/ 00( . )
C07C 69/ 708( . )
C07C 217/ 08( . )
C07C 235/ 06( . )
C07D 207/ 46( . )
C07D 243/ 32( . )
C07K 16/ 28( . )
C07K 17/ 06( . )
G01N 33/ 532( . )
(86) International application number:
PCT/SE1991/000497
(87) International publication number:
WO 1992/001474 (06.02.1992 Gazette 1992/04)
(84) Designated Contracting States:
AT BE CH DE DK ES FR GB GR IT LI LU NL SE

(30) Priority: 20.07.1990 SE 19900002484
20.07.1990 SE 19900002490

(71) Applicant: Kabi Pharmacia AB
S-751 82 Uppsala (SE)

(72) Inventors:
  • AGBACK, Hubert
    S-755 90 Uppsala (SE)
  • AHRGREN, Leif
    S-740 60 Örbyhus (SE)
  • HARALDSSON, Martin
    S-186 51 Vallentuna (SE)
  • KERBLOM, Eva
    S-752 52 Uppsala (SE)

(74) Representative: Widén, Björn, et al 
Pharmacia AB
S-751 82 Uppsala
S-751 82 Uppsala (SE)

   


(54) HETEROBIFUNCTIONAL REAGENTS AND CONJUGATES WITH OXAALKYLENE UNITS FOR AMPHIPHILIC BRIDGE STRUCTURES