(19)
(11) EP 0 540 663 A1

(12)

(43) Date of publication:
12.05.1993 Bulletin 1993/19

(21) Application number: 91914889.0

(22) Date of filing: 25.07.1991
(51) International Patent Classification (IPC): 
A61K 38/ 00( . )
A61P 37/ 08( . )
C07K 14/ 52( . )
C12P 21/ 02( . )
A61K 38/ 20( . )
C07K 14/ 00( . )
C07K 14/ 54( . )
(86) International application number:
PCT/US1991/005274
(87) International publication number:
WO 1992/001465 (06.02.1992 Gazette 1992/04)
(84) Designated Contracting States:
AT BE CH DE DK ES FR GB GR IT LI LU NL SE

(30) Priority: 25.07.1990 US 19900558004

(71) Applicant: BOARD OF REGENTS THE UNIVERSITY OF TEXAS SYSTEM
Austin, Texas 78701 (US)

(72) Inventors:
  • ALAM, Rafeul
    Galveston, TX 77551 (US)
  • LETT-BROWN, Michael, A.
    Galveston, TX 77550 (US)
  • GRANT, J., Andrew
    Galveston, TX 77551 (US)

(74) Representative: Dost, Wolfgang, Dr.rer.nat., Dipl.-Chem., et al 
Patent- und Rechtsanwälte Bardehle . Pagenberg . Dost . Altenburg . Frohwitter . Geissler & Partner Postfach 86 06 20
D-81633 München
D-81633 München (DE)

   


(54) INTERLEUKIN 8 INHIBITION OF CYTOKINE-INDUCED HISTAMINE RELEASE FROM BOSOPHILS OR MAST CELLS