(19)
(11) EP 0 542 753 A1

(12)

(43) Date of publication:
26.05.1993 Bulletin 1993/21

(21) Application number: 91910584.0

(22) Date of filing: 10.05.1991
(51) International Patent Classification (IPC): 
C07K 14/ 02( . )
A61K 39/ 00( . )
(86) International application number:
PCT/US1991/003268
(87) International publication number:
WO 1991/017768 (28.11.1991 Gazette 1991/27)
(84) Designated Contracting States:
AT BE CH DE DK ES FR GB GR IT LI LU NL SE

(30) Priority: 11.05.1990 US 19900522663

(71) Applicant: SCRIPPS CLINIC AND RESEARCH FOUNDATION
La Jolla California 92037 (US)

(72) Inventors:
  • MILICH, David, R.
    Mira Mesa, CA 92126 (US)
  • THORNTON, George, B.
    San Diego, CA 92127 (US)

(74) Representative: Fisher, Adrian John, et al 
CARPMAELS & RANSFORD 43 Bloomsbury Square
London WC1A 2RA
London WC1A 2RA (GB)

   


(54) EPITOPES OF THE PRE-S REGION OF HEPATITIS B VIRUS SURFACE ANTIGEN