(19)
(11)
EP 0 542 753 A1
(12)
(43)
Date of publication:
26.05.1993
Bulletin 1993/21
(21)
Application number:
91910584.0
(22)
Date of filing:
10.05.1991
(51)
International Patent Classification (IPC):
C07K
14/
02
( . )
A61K
39/
00
( . )
(86)
International application number:
PCT/US1991/003268
(87)
International publication number:
WO 1991/017768
(
28.11.1991
Gazette 1991/27)
(84)
Designated Contracting States:
AT BE CH DE DK ES FR GB GR IT LI LU NL SE
(30)
Priority:
11.05.1990
US 19900522663
(71)
Applicant:
SCRIPPS CLINIC AND RESEARCH FOUNDATION
La Jolla California 92037 (US)
(72)
Inventors:
MILICH, David, R.
Mira Mesa, CA 92126 (US)
THORNTON, George, B.
San Diego, CA 92127 (US)
(74)
Representative:
Fisher, Adrian John, et al
CARPMAELS & RANSFORD 43 Bloomsbury Square
London WC1A 2RA
London WC1A 2RA (GB)
(54)
EPITOPES OF THE PRE-S REGION OF HEPATITIS B VIRUS SURFACE ANTIGEN