N-HYDROCARBYL-4-SUBSTITUTED PIPERIDINES, THEIR PREPARATION AND USE AS CALCIUM BLOCKING AGENTS - Patent 0542846

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EP 0 542 846 A1

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(43)	Date of publication:
	26.05.1993 Bulletin 1993/21

(21)	Application number: 91914558.0

(22)	Date of filing: 05.08.1991

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International Patent Classification (IPC):

A61K 31/ 445^{( . )}
A61P 9/ 08^{( . )}
A61P 25/ 04^{( . )}
A61P 25/ 28^{( . )}
C07D 211/ 20^{( . )}
C07D 211/ 26^{( . )}
C07D 405/ 12^{( . )}

A61K 31/ 451^{( . )}
A61P 9/ 10^{( . )}
A61P 25/ 08^{( . )}
C07D 211/ 14^{( . )}
C07D 211/ 22^{( . )}
C07D 211/ 46^{( . )}

(86)	International application number:
	PCT/GB1991/001340

(87)	International publication number:
	WO 1992/002502 (20.02.1992 Gazette 1992/05)

(84)	Designated Contracting States:
	AT BE CH DE DK ES FR GB GR IT LI LU NL SE

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Priority:

06.08.1990 GB 19900017224
12.04.1991 GB 19910007757

(71)	Applicant: SMITH KLINE & FRENCH LABORATORIES LIMITED
	Welwyn Garden City Hertfordshire, AL7 1EY (GB)

(72)	Inventors:
	BROWN, Thomas, Henry SmithKline Beecham Harlow Essex CM19 5AD (GB) COOPER, David, Gwynn SmithKline Beecham Harlow Essex CM19 5AD (GB)

(74)	Representative: Florence, Julia Anne, et al
	SmithKline Beecham plc Corporate Intellectual Property SB House Great West Road Brentford, Middlesex TW8 9BD Brentford, Middlesex TW8 9BD (GB)

(54)	N-HYDROCARBYL-4-SUBSTITUTED PIPERIDINES, THEIR PREPARATION AND USE AS CALCIUM BLOCKING AGENTS