PURINE BASE MODIFIED 2'-DEOXYRIBONUCLEOSIDES, USE IN TRIPLEX FORMING OLIGONUCLEOTIDES AND PROCESS FOR PREPARING THE SAME - Patent 0543004

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EP 0 543 004 A1

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(43)	Date of publication:
	26.05.1993 Bulletin 1993/21

(21)	Application number: 92914426.0

(22)	Date of filing: 04.06.1992

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International Patent Classification (IPC):

A61K 31/ 70^{( . )}
A61K 31/ 7052^{( . )}
A61K 31/ 708^{( . )}
A61K 31/ 7135^{( . )}
C07F 7/ 08^{( . )}
C07H 19/ 16^{( . )}
C07H 19/ 23^{( . )}
C07H 23/ 00^{( . )}
C12Q 1/ 68^{( . )}

A61K 31/ 7042^{( . )}
A61K 31/ 7076^{( . )}
A61K 31/ 7088^{( . )}
A61P 31/ 12^{( . )}
C07H 19/ 04^{( . )}
C07H 19/ 20^{( . )}
C07H 21/ 04^{( . )}
C12N 15/ 09^{( . )}

(86)	International application number:
	PCT/US1992/004795

(87)	International publication number:
	WO 1992/021690 (10.12.1992 Gazette 1992/31)

(84)	Designated Contracting States:
	AT BE CH DE DK ES FR GB GR IT LI LU MC NL SE

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Priority:

05.06.1991 US 19910712151

(71)	Applicants:
	TRIPLEX PHARMACEUTICAL CORPORATION The Woodlands, TX 77380 (US) BAYLOR COLLEGE OF MEDICINE Houston, TX 77030 (US)

(72)	Inventors:
	REVANKAR, Ganapathi, Ramakrishna The Woodlands, TX 77381 (US) HOGAN, Michael, Edward The Woodlands, TX 77381 (US) RAO, Takkellapati, Sudhakar The Woodlands, TX 77380 (US) SHROFF, Hitesh, Navinchandra The Woodlands, TX 77381 (US)

(74)	Representative: Wise, Stephen James, et al
	c/o RAWORTH, MOSS & COOK 36 Sydenham Road Croydon, Surrey CR0 2EF Croydon, Surrey CR0 2EF (GB)

(54)	PURINE BASE MODIFIED 2'-DEOXYRIBONUCLEOSIDES, USE IN TRIPLEX FORMING OLIGONUCLEOTIDES AND PROCESS FOR PREPARING THE SAME