(19)
(11) EP 0 543 919 A1

(12)

(43) Date of publication:
02.06.1993 Bulletin 1993/22

(21) Application number: 91915773.0

(22) Date of filing: 22.07.1991
(51) International Patent Classification (IPC): 
A61K 31/ 135( . )
A61K 31/ 22( . )
A61K 31/ 343( . )
A61K 31/ 352( . )
A61K 31/ 381( . )
A61K 31/ 385( . )
A61K 31/ 40( . )
A61K 31/ 4433( . )
A61K 31/ 495( . )
A61K 31/ 55( . )
A61P 25/ 00( . )
C07D 209/ 08( . )
C07D 311/ 58( . )
C07D 333/ 54( . )
C07D 339/ 08( . )
C07D 413/ 06( . )
 A61K 31/ 215( . )
A61K 31/ 34( . )
A61K 31/ 35( . )
A61K 31/ 38( . )
A61K 31/ 382( . )
A61K 31/ 39( . )
A61K 31/ 415( . )
A61K 31/ 445( . )
A61K 31/ 535( . )
A61P 9/ 10( . )
A61P 25/ 18( . )
C07D 307/ 79( . )
C07D 327/ 06( . )
C07D 335/ 06( . )
C07D 409/ 06( . )
(86) International application number:
PCT/US1991/005028
(87) International publication number:
WO 1992/003131 (05.03.1992 Gazette 1992/06)
(84) Designated Contracting States:
AT BE CH DE DK ES FR GB GR IT LI LU NL SE

(30) Priority: 13.08.1990 US 19900566744

(71) Applicant: G.D. SEARLE & CO.
Chicago IL 60680-5110 (US)

(72) Inventors:
  • ROBA, Joseph, L.
    B-1325 Dion-Valmont (BE)
  • GILLET, Claude, L.
    B-5860 Blanmont (BE)
  • RAFFERTY, Michel, F.
    Buffalo Grove, IL 60089 (US)
  • JARROT, Bevyn
    Diamond Creek, VIC 3089 (AU)
  • BEART, Philip, Mark
    Ivanhoe, VIC 3079 (AU)

(74) Representative: Beil, Hans Chr., Dr. 
BEIL, WOLFF & BEIL, Rechtsanwälte, Postfach 80 01 40
D-65901 Frankfurt
D-65901 Frankfurt (DE)

   


(54) USE OF HETEROCYCLIC AMINO-ALCOHOL COMPOUNDS FOR TREATMENT OF CNS DISEASES