COLONIC-TARGETED ORAL DRUG-DOSAGE FORMS BASED ON CROSSLINKED HYDROGELS CONTAINING AZOBONDS AND EXHIBITING pH-DEPENDENT SWELLING - Patent 0544671

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(11)

EP 0 544 671 A1

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(43)	Date of publication:
	09.06.1993 Bulletin 1993/23

(21)	Application number: 91907661.0

(22)	Date of filing: 03.04.1991

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International Patent Classification (IPC):

A61K 9/ 20^{( . )}
A61K 47/ 48^{( . )}
C08F 20/ 26^{( . )}
C08F 20/ 42^{( . )}
C08F 26/ 10^{( . )}
C08F 212/ 12^{( . )}
C08F 218/ 08^{( . )}
C08F 220/ 06^{( . )}
C08F 220/ 36^{( . )}
C08F 220/ 58^{( . )}
C08F 222/ 06^{( . )}
C08F 246/ 00^{( . )}
C08L 33/ 00^{( . )}

A61K 47/ 32^{( . )}
C08F 20/ 02^{( . )}
C08F 20/ 34^{( . )}
C08F 20/ 52^{( . )}
C08F 212/ 00^{( . )}
C08F 218/ 02^{( . )}
C08F 220/ 04^{( . )}
C08F 220/ 28^{( . )}
C08F 220/ 46^{( . )}
C08F 220/ 60^{( . )}
C08F 226/ 10^{( . )}
C08L 31/ 04^{( . )}
C08L 33/ 04^{( . )}

(86)	International application number:
	PCT/US1991/002319

(87)	International publication number:
	WO 1991/016057 (31.10.1991 Gazette 1991/25)

(84)	Designated Contracting States:
	AT BE CH DE DK ES FR GB GR IT LI LU NL SE

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Priority:

18.04.1990 US 19900513267

(71)	Applicant: THE UNIVERSITY OF UTAH
	Salt Lake City, Utah 84112 (US)

(72)	Inventors:
	KOPECEK, Jindrich Salt Lake City, UT 84102 (US) KIM, Sung, Wan Salt Lake City, UT 84117 (US) BRONDSTED, Helle Salt Lake City, UT 84103 (US) KOPECKOVA, Pavla Salt Lake City, UT 84102 (US)

(74)	Representative: Goldin, Douglas Michael, et al
	J.A. KEMP & CO. 14, South Square Gray's Inn London WC1R 5LX London WC1R 5LX (GB)

(54)	COLONIC-TARGETED ORAL DRUG-DOSAGE FORMS BASED ON CROSSLINKED HYDROGELS CONTAINING AZOBONDS AND EXHIBITING pH-DEPENDENT SWELLING