(19)

(11)

EP 0 544 751 A1

(12)

(43) Date of publication: 09.06.1993 Bulletin 1993/23 (21) Application number: 91915097.0 (22) Date of filing: 20.08.1991

(51) International Patent Classification (IPC):  A01N( . ) A01N 25/ 00( . ) A01N 25/ 22( . ) A01N 53/ 08( . ) A01N 57/ 16( . ) A01N 25/ 02( . ) A01N 25/ 04( . ) A01N 53/ 00( . ) A01N 57/ 08( . ) (86) International application number: PCT/GB1991/001413 (87) International publication number: WO 1992/003047 (05.03.1992 Gazette 1992/06)

(84) Designated Contracting States: AT BE CH DE DK ES FR GB GR IT LI LU NL SE (30) Priority: 20.08.1990 GB 19900018227 (71) Applicant: THE WELLCOME FOUNDATION LIMITED London NW1 2BP (GB)	(72) Inventors: CRAMPTON, Peter Leslie Berkhamsted, Hertfordshire HP4 2DY (GB) HUSON, Andrew John Berkhamsted, Hertfordshire HP4 2DY (GB) JEFFRIES, David Alan Berkhamsted, Hertfordshire HP4 2DY (GB) (74) Representative: Vieillefosse, Jean-Claude  ROUSSEL UCLAF Département des Brevets 111, Route de Noisy F-93235 Romainville Cedex F-93235 Romainville Cedex (FR)