(19)

(11)

EP 0 546 031 A1

(12)

(43) Date of publication: 16.06.1993 Bulletin 1993/24 (21) Application number: 91915656.0 (22) Date of filing: 16.08.1991

(51) International Patent Classification (IPC):  C07K 14/ 085( . ) A61K 39/ 00( . ) C07K 14/ 18( . ) (86) International application number: PCT/SE1991/000542 (87) International publication number: WO 1992/003475 (05.03.1992 Gazette 1992/06)

(84) Designated Contracting States: AT BE CH DE DK ES FR GB GR IT LI LU NL SE (30) Priority: 16.08.1990 SE 19900002671 (71) Applicant: REPLICO MEDICAL AB S-234 00 Lomma (SE)	(72) Inventors: BLOMBERG, Jonas S-234 00 Lomma (SE) PIPKORN, Rüdiger D-6900 Heidelberg (DE) (74) Representative: Rostovanyi, Peter  AWAPATENT AB, Box 5117 S-200 71 Malmö S-200 71 Malmö (SE)