PROTEASES CAUSING ABNORMAL DEGRADATION OF AMYLOID $g(b)-PROTEIN PRECURSOR - Patent 0546084

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EP 0 546 084 A1

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(43)	Date of publication:
	16.06.1993 Bulletin 1993/24

(21)	Application number: 91916872.0

(22)	Date of filing: 19.08.1991

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International Patent Classification (IPC):

A61K 38/ 55^{( . )}
C07K 14/ 47^{( . )}
G01N 33/ 15^{( . )}

A61P 25/ 28^{( . )}
C12N 9/ 64^{( . )}
G01N 33/ 50^{( . )}

(86)	International application number:
	PCT/US1991/005932

(87)	International publication number:
	WO 1992/003542 (05.03.1992 Gazette 1992/06)

(84)	Designated Contracting States:
	AT BE CH DE DK ES FR GB GR IT LI LU NL SE

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Priority:

17.08.1990 US 19900568806

(71)	Applicant: BOSTON UNIVERSITY
	Boston, MA 02215 (US)

(72)	Inventor:
	ABRAHAM, Carmela, R. Lexington, MA 02173 (US)

(74)	Representative: Deans, Michael John Percy
	Lloyd Wise, Tregear & CO. Norman House 105-109 Strand London WC2R OAE London WC2R OAE (GB)

(54)	PROTEASES CAUSING ABNORMAL DEGRADATION OF AMYLOID $g(b)-PROTEIN PRECURSOR