(19)
(11) EP 0 548 178 A1

(12)

(43) Date of publication:
30.06.1993 Bulletin 1993/26

(21) Application number: 91916341.0

(22) Date of filing: 01.08.1991
(51) International Patent Classification (IPC): 
G01N 30/ 86( . )
C07K 16/ 06( . )
G01N 30/ 02( . )
C07K 1/ 22( . )
G01N 30/ 62( . )
G01N 30/ 88( . )
(86) International application number:
PCT/US1991/005544
(87) International publication number:
WO 1992/002815 (20.02.1992 Gazette 1992/05)
(84) Designated Contracting States:
AT BE CH DE DK ES FR GB GR IT LI LU NL SE

(30) Priority: 10.08.1990 US 19900566121

(71) Applicant: PERSEPTIVE BIOSYSTEMS, INC.
Cambridge, MA 02139 (US)

(72) Inventors:
  • AFEYAN, Noubar, B.
    Brookline, MA 02146 (US)
  • REGNIER, Fred, E.
    West Lafayette, IN 47906 (US)

(74) Representative: Holdcroft, James Gerald, Dr. 
Graham Watt & Co., Riverhead
Sevenoaks, Kent TN13 2BN
Sevenoaks, Kent TN13 2BN (GB)

   


(54) QUANTITATIVE ANALYSIS AND MONITORING OF PROTEIN STRUCTURE BY SUBTRACTIVE CHROMATOGRAPHY