CARBOXYLIC ACID ESTERS OF RAPAMYCIN - Patent 0549727

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EP 0 549 727 A1

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(43)	Date of publication:
	07.07.1993 Bulletin 1993/27

(21)	Application number: 91919248.0

(22)	Date of filing: 19.09.1991

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International Patent Classification (IPC):

A61K 31/ 435^{( . )}
A61P 29/ 00^{( . )}
C07D 498/ 18^{( . )}
C07K 5/ 06^{( . )}

A61P 9/ 12^{( . )}
A61P 31/ 00^{( . )}
C07H 19/ 01^{( . )}
A61K 38/ 00^{( . )}

(86)	International application number:
	PCT/US1991/006824

(87)	International publication number:
	WO 1992/005179 (02.04.1992 Gazette 1992/08)

(84)	Designated Contracting States:
	AT BE CH DE DK ES FR GB GR IT LI LU NL SE

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Priority:

19.09.1990 US 19900584833
28.09.1990 US 19900589878
19.02.1991 US 19910657294

(71)	Applicant: AMERICAN HOME PRODUCTS CORPORATION
	Madison, New Jersey 07940-0874 (US)

(72)	Inventors:
	CAUFIELD, Craig, Eugene Plainsboro, NJ 08536 (US) FAILLI, Amedeo, Arturo Princeton Junction, NJ 08550 (US) STEFFAN, Robert, John Langhorne, PA 19047 (US)

(74)	Representative: Wileman, David Francis, Dr., et al
	c/o Wyeth Laboratories Huntercombe Lane South Taplow Maidenhead Berkshire SL6 OPH Taplow Maidenhead Berkshire SL6 OPH (GB)

(54)	CARBOXYLIC ACID ESTERS OF RAPAMYCIN