(19)

(11)

EP 0 550 446 A1

(12)

(43) Date of publication: 14.07.1993 Bulletin 1993/28 (21) Application number: 91913806.0 (22) Date of filing: 27.07.1991

(51) International Patent Classification (IPC):  A61K 31/ 135( . ) A61K 31/ 315( . ) A61K 31/ 495( . ) A61K 31/ 275( . ) A61K 31/ 44( . ) A61K 31/ 55( . ) (86) International application number: PCT/EP1991/001410 (87) International publication number: WO 1993/002670 (18.02.1993 Gazette 1993/05)

(84) Designated Contracting States: AT BE CH DE DK ES FR GB GR IT LI LU NL SE (71) Applicant: BAYER AG D-51368 Leverkusen (DE)	(72) Inventor: FLOERSHEIM, Georges CH-4052 Basel (CH)