(19)
(11) EP 0 550 502 A1

(12)

(43) Date of publication:
14.07.1993 Bulletin 1993/28

(21) Application number: 91916375.0

(22) Date of filing: 10.09.1991
(51) International Patent Classification (IPC): 
A61K 31/ 415( . )
A61P 7/ 02( . )
A61P 9/ 10( . )
A61P 43/ 00( . )
C07D 233/ 64( . )
C07D 235/ 02( . )
C07D 403/ 12( . )
C07D 405/ 12( . )
C07D 409/ 04( . )
C07F 9/ 6506( . )
A61K 31/ 675( . )
A61P 9/ 08( . )
A61P 29/ 00( . )
C07D 233/ 54( . )
C07D 233/ 84( . )
C07D 403/ 06( . )
C07D 405/ 04( . )
C07D 405/ 14( . )
C07D 409/ 14( . )
(86) International application number:
PCT/GB1991/001546
(87) International publication number:
WO 1992/004330 (19.03.1992 Gazette 1992/07)
(84) Designated Contracting States:
BE CH DE FR GB IT LI NL

(30) Priority: 11.09.1990 GB 19900019840

(71) Applicant: SMITH KLINE & FRENCH LABORATORIES LIMITED
Welwyn Garden City Hertfordshire, AL7 1EY (GB)

(72) Inventors:
  • HICKEY, Deirdre Mary Bernadette
    Welwyn, Hertfordshire AL6 9AR (GB)
  • COOPER, David Gwynn, c/o SmithKline Beecham
    Harlow, Essex CM19 5AD (GB)
  • WHITTAKER, Caroline Marie
    Welwyn, Hertfordshire AL6 9AR (GB)

(74) Representative: Giddings, Peter John, Dr., et al 
SmithKline Beecham plc Corporate Intellectual Property SB House Great West Road
Brentford, Middlesex TW8 9BD
Brentford, Middlesex TW8 9BD (GB)

   


(54) SUBSTITUTED IMIDAZOLES, THEIR PREPARATION AND PHARMACEUTICAL COMPOSITIONS