(19)
(11) EP 0 550 629 A1

(12)

(43) Date of publication:
14.07.1993 Bulletin 1993/28

(21) Application number: 91917895.0

(22) Date of filing: 16.08.1991
(51) International Patent Classification (IPC): 
A61K 38/ 27( . )
C07K 14/ 00( . )
C07K 14/ 575( . )
C07K 14/ 705( . )
C12N 15/ 09( . )
C12P 21/ 02( . )
A61K 38/ 00( . )
C07K 1/ 107( . )
C07K 14/ 435( . )
C07K 14/ 61( . )
C07K 14/ 72( . )
C12N 15/ 12( . )
G01N 33/ 76( . )
(86) International application number:
PCT/US1991/005856
(87) International publication number:
WO 1992/003478 (05.03.1992 Gazette 1992/06)
(84) Designated Contracting States:
AT BE CH DE DK ES FR GB GR IT LI LU NL SE

(30) Priority: 17.08.1990 US 19900568936

(71) Applicant: GENENTECH, INC.
South San Francisco California 94080 (US)

(72) Inventors:
  • BASS, Steven, H.
    Redwood City, CA 94061 (US)
  • CUNNINGHAM, Brian, C.
    Piedmont, CA 94611 (US)
  • FUH, Germaine
    San Francisco, CA 94116 (US)
  • LOWMAN, Henry, B.
    Hercules, CA 94547 (US)
  • MATTHEWS, David, J.
    San Francisco, CA 94122 (US)
  • WELLS, James, A.
    Burlingame, CA 94010 (US)

(74) Representative: Stuart, Ian Alexander, et al 
MEWBURN ELLIS York House 23 Kingsway
London WC2B 6HP
London WC2B 6HP (GB)

   


(54) METAL ION MEDIATED RECEPTOR BINDING OF POLYPEPTIDE HORMONES