(19)
(11)
EP 0 551 294 A1
(12)
(43)
Date of publication:
21.07.1993
Bulletin 1993/29
(21)
Application number:
91915940.0
(22)
Date of filing:
01.08.1991
(51)
International Patent Classification (IPC):
C07K
14/
82
( . )
C12N
15/
113
( . )
(86)
International application number:
PCT/US1991/005443
(87)
International publication number:
WO 1993/003141
(
18.02.1993
Gazette 1993/05)
(84)
Designated Contracting States:
DE FR GB
(71)
Applicant:
CITY OF HOPE
Duarte California 91010-0269 (US)
(72)
Inventors:
SNYDER, David, S.
Arcadia, CA 91006 (US)
ROSSI, John, J.
Glendora, CA 91740 (US)
FORMAN, Stephen, J.
San Marino, CA 91108 (US)
(74)
Representative:
Roberts, Alison Christine, et al
Kilburn & Strode, 30 John Street
London WC1N 2DD
London WC1N 2DD (GB)
(54)
RIBOZYME INHIBITION OF BCR-ABL GENE EXPRESSION