(19)

(11)

EP 0 551 383 A1

(12)

(43) Date of publication: 21.07.1993 Bulletin 1993/29 (21) Application number: 91918249.0 (22) Date of filing: 20.09.1991

(51) International Patent Classification (IPC):  A61F 2/ 14( . ) A61L 27/ 00( . ) A61L 27/ 34( . ) C08F 291/ 00( . ) G02B 1/ 04( . ) B05D 3/ 06( . ) A61F 2/ 16( . ) A61L 27/ 16( . ) B05D 7/ 02( . ) C08J 7/ 18( . ) A61F 2/ 00( . ) (86) International application number: PCT/US1991/006729 (87) International publication number: WO 1992/005694 (16.04.1992 Gazette 1992/09)

(84) Designated Contracting States: GB (30) Priority: 05.10.1990 US 19900592483 (71) Applicant: UNIVERSITY OF FLORIDA Gainesville, Florida 32611-2037 (US)

(72) Inventors: GOLDBERG, Eugene, P. Dept. of Materials Sci. Gainesville, FL 32611 (US) BURNS, James, W. Holliston, MA 01746 (US) KUMAR, G., Sudesh Alchemie Research Center Thane 400 601 Maharastra (IN) OSBORN, David, C. Manchester, MD 63021 (US) LARSON, Jeffrey, A. San Diego, CA 92128 (US) SHEETS, John, W. Pasadena, CA 91711 (US) YAHIAOUI, Ali Department of Materials Science Gainesville, FL 32611 (US) ROBINSON, Richard Gainesville, FL 32602 (US) (74) Representative: Hedley, Nicholas James Matthew  Stephenson Harwood One, St. Paul's Churchyard London EC4M 8SH London EC4M 8SH (GB)