(19)
(11) EP 0 551 434 A1

(12)

(43) Date of publication:
21.07.1993 Bulletin 1993/29

(21) Application number: 91919917.0

(22) Date of filing: 27.09.1991
(51) International Patent Classification (IPC): 
A61K 31/ 135( . )
A61K 51/ 00( . )
C07B 59/ 00( . )
A61K 31/ 138( . )
A61P 35/ 00( . )
C07C 217/ 18( . )
(86) International application number:
PCT/US1991/007150
(87) International publication number:
WO 1992/006068 (16.04.1992 Gazette 1992/09)
(84) Designated Contracting States:
AT BE CH DE DK ES FR GB GR IT LI LU NL SE

(30) Priority: 01.10.1990 US 19900589928
28.06.1991 US 19910722322

(71) Applicant: BOARD OF REGENTS, THE UNIVERSITY OF TEXAS SYSTEM
Austin, TX 78701 (US)

(72) Inventors:
  • YANG, David
    Sugarland, TX 77478 (US)
  • WALLACE, Sidney
    Houston, TX 77005 (US)

(74) Representative: Allard, Susan Joyce 
BOULT, WADE & TENNANT 27 Furnival Street
London EC4A 1PQ
London EC4A 1PQ (GB)

   


(54) HIGH AFFINITY TAMOXIFEN DERIVATIVES AND USES THEREOF