(19)
(11)
EP 0 551 434 A1
(12)
(43)
Date of publication:
21.07.1993
Bulletin 1993/29
(21)
Application number:
91919917.0
(22)
Date of filing:
27.09.1991
(51)
International Patent Classification (IPC):
A61K
31/
135
( . )
A61K
51/
00
( . )
C07B
59/
00
( . )
A61K
31/
138
( . )
A61P
35/
00
( . )
C07C
217/
18
( . )
(86)
International application number:
PCT/US1991/007150
(87)
International publication number:
WO 1992/006068
(
16.04.1992
Gazette 1992/09)
(84)
Designated Contracting States:
AT BE CH DE DK ES FR GB GR IT LI LU NL SE
(30)
Priority:
01.10.1990
US 19900589928
28.06.1991
US 19910722322
(71)
Applicant:
BOARD OF REGENTS, THE UNIVERSITY OF TEXAS SYSTEM
Austin, TX 78701 (US)
(72)
Inventors:
YANG, David
Sugarland, TX 77478 (US)
WALLACE, Sidney
Houston, TX 77005 (US)
(74)
Representative:
Allard, Susan Joyce
BOULT, WADE & TENNANT 27 Furnival Street
London EC4A 1PQ
London EC4A 1PQ (GB)
(54)
HIGH AFFINITY TAMOXIFEN DERIVATIVES AND USES THEREOF