N-(2-ALKYL-3-MERCAPTOGLUTARYL)-AMINO-DIAZA CYCLOALKANONE DERIVATIVES AND THEIR USE AS COLLAGENASE INHIBITORS - Patent 0552264

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EP 0 552 264 A1

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(43)	Date of publication:
	28.07.1993 Bulletin 1993/30

(21)	Application number: 91919268.0

(22)	Date of filing: 09.10.1991

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International Patent Classification (IPC):

A61K 31/ 395^{( . )}
A61P 43/ 00^{( . )}
C07D 245/ 02^{( . )}

A61K 31/ 55^{( . )}
C07D 243/ 08^{( . )}
C07D 247/ 00^{( . )}

(86)	International application number:
	PCT/GB1991/001749

(87)	International publication number:
	WO 1992/006966 (30.04.1992 Gazette 1992/10)

(84)	Designated Contracting States:
	AT BE CH DE DK ES FR GB GR IT LI LU NL SE

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Priority:

11.10.1990 GB 19900022117

(71)	Applicant: BEECHAM GROUP plc
	Brentford Middlesex TW8 9EP (GB)

(72)	Inventors:
	MARKWELL, Roger, Edward SmithKline Beecham Pharm. Harlow Essex CM19 5AD (GB) WARD, Robert, William SmithKline Beecham Pharma. Harlow Essex CM19 5AD (GB) RAHMAN, Shahzad, Sharooq SmithKline Beecham Phar. Harlow Essex CM19 5AD (GB)

(74)	Representative: Giddings, Peter John, Dr., et al
	SmithKline Beecham plc Corporate Intellectual Property SB House Great West Road Brentford, Middlesex TW8 9BD Brentford, Middlesex TW8 9BD (GB)

(54)	N-(2-ALKYL-3-MERCAPTOGLUTARYL)-AMINO-DIAZA CYCLOALKANONE DERIVATIVES AND THEIR USE AS COLLAGENASE INHIBITORS