ACETYLENES DISUBSTITUTED WITH A HETEROAROMATIC GROUP AND A 2-SUBSTITUTED CHROMANYL, THIOCHROMANYL OR 1,2,3,4-TETRAHYDROQUINOLINYL GROUP HAVING RETINOID-LIKE ACTIVITY - Patent 0555235

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(11)

EP 0 555 235 A1

(12)

(43)	Date of publication:
	18.08.1993 Bulletin 1993/33

(21)	Application number: 91917319.0

(22)	Date of filing: 24.09.1991

(51)

International Patent Classification (IPC):

A61K 31/ 35^{( . )}
A61K 31/ 42^{( . )}
A61K 31/ 44^{( . )}
A61K 31/ 4433^{( . )}
A61K 31/ 50^{( . )}
A61P 17/ 00^{( . )}
A61P 35/ 00^{( . )}
C07D 407/ 06^{( . )}
C07D 413/ 06^{( . )}

A61K 31/ 38^{( . )}
A61K 31/ 425^{( . )}
A61K 31/ 443^{( . )}
A61K 31/ 495^{( . )}
A61K 31/ 505^{( . )}
A61P 27/ 02^{( . )}
C07D 405/ 06^{( . )}
C07D 409/ 06^{( . )}
C07D 417/ 06^{( . )}

(86)	International application number:
	PCT/US1991/006900

(87)	International publication number:
	WO 1992/006092 (16.04.1992 Gazette 1992/09)

(84)	Designated Contracting States:
	AT BE CH DE DK ES FR GB GR IT LI LU NL SE

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Priority:

09.10.1990 US 19900595128

(71)	Applicant: ALLERGAN, INC.
	Irvine, California 92713-9534 (US)

(72)	Inventor:
	CHANDRARATNA, Roshantha, A., S. El Toro, CA 92630 (US)

(74)	Representative: Griffin, Kenneth David, et al
	Saunders & Dolleymore 9, Rickmansworth Road Watford Hertfordshire WD1 7HE Watford Hertfordshire WD1 7HE (GB)

(54)	ACETYLENES DISUBSTITUTED WITH A HETEROAROMATIC GROUP AND A 2-SUBSTITUTED CHROMANYL, THIOCHROMANYL OR 1,2,3,4-TETRAHYDROQUINOLINYL GROUP HAVING RETINOID-LIKE ACTIVITY