ATBECHDEDKESFRGBGRITLILUNLSE........................................................................*EPregister to ST.36 EBD process v 1.0 kbaumeister@epo.org (15 Jan 2013)0555235A119930818EP91917319.01991092419930408enenen1990059512819901009US1993081819933319930818199333

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enACETYLENES DISUBSTITUTED WITH A HETEROAROMATIC GROUP AND A 2-SUBSTITUTED CHROMANYL, THIOCHROMANYL OR 1,2,3,4-TETRAHYDROQUINOLINYL GROUP HAVING RETINOID-LIKE ACTIVITYfrACETYLENES DISUBSTITUES PAR UN GROUPE HETEROAROMATIQUE ET UN GROUPE CHROMANYL A SUBSTITUTION EN POSITION 2, THIOCHROMANYL OU 1,2,3,4-TETRAHYDROQUINOLINYL PRESENTANT UNE ACTIVITE DE TYPE RETINOIDEdeDISUBSTITUIERTE ACETYLENE MIT EINER HETEROAROMATISCHEN GRUPPE UND EINER 2-SUBSTITUIERTEN CHROMANYL-, THIOCHROMANYL- ODER 1,2,3,4-TETRAHYDROCHINOLINYLGRUPPE, DIE RETINOIDÄHNLICHE WIRKUNG BESITZENALLERGAN, INC.2525 Dupont Drive, P.O. Box 19534Irvine, California 92713-9534USCHANDRARATNA, Roshantha, A., S.23015 AshwoodEl Toro, CA 92630USGriffin, Kenneth David, et alSaunders & Dolleymore 9, Rickmansworth RoadWatford Hertfordshire WD1 7HEGBATBECHDEDKESFRGBGRITLILUNLSEUS199100690019910924enWO199200609219920416199209