DNA CAPABLE OF SITE-SPECIFIC INTEGRATION INTO MYCOBACTERIA

(19)

(11)

EP 0 556 182 A1

(12)

(43)	Date of publication:
	25.08.1993 Bulletin 1993/34

(21)	Application number: 91914084.0

(22)	Date of filing: 09.07.1991

(51)

International Patent Classification (IPC):

A61K 39/ 04^{( . )}
C07K 14/ 16^{( . )}
C12N 15/ 09^{( . )}
C12N 15/ 90^{( . )}
A61K 38/ 00^{( . )}
C12R 1/ 32^{( . )}

A61P 31/ 04^{( . )}
C12N 1/ 21^{( . )}
C12N 15/ 74^{( . )}
C12P 21/ 02^{( . )}
A61K 39/ 00^{( . )}

(86)	International application number:
	PCT/US1991/004833

(87)	International publication number:
	WO 1992/001783 (06.02.1992 Gazette 1992/04)

(84)	Designated Contracting States:
	AT BE CH DE DK ES FR GB GR IT LI LU NL SE

(30)

Priority:

16.07.1990 US 19900553907

(71)	Applicants:
	ALBERT EINSTEIN COLLEGE OF MEDICINE OF YESHIVA UNIVERSITY Bronx New York 10461 (US) UNIVERSITY OF PITTSBURGH Pittsburgh, Pennsylvania 15260 (US)

(72)	Inventors:
	JACOBS, William, R. City Island, NY 10464 (US) HATFULL, Graham Pittsburgh, PA 15217 (US)

(74)	Representative: LOUIS, PÖHLAU, LOHRENTZ & SEGETH
	Postfach 3055 D-90014 Nürnberg D-90014 Nürnberg (DE)

(54)	DNA CAPABLE OF SITE-SPECIFIC INTEGRATION INTO MYCOBACTERIA