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(11)

EP 0 557 424 A1

(12)

(43) Date of publication: 01.09.1993 Bulletin 1993/35 (21) Application number: 92900490.0 (22) Date of filing: 14.11.1991

(51) International Patent Classification (IPC):  C07K 14/ 705( . ) (86) International application number: PCT/US1991/008512 (87) International publication number: WO 1992/008490 (29.05.1992 Gazette 1992/12)

(84) Designated Contracting States: CH DE FR GB LI (30) Priority: 16.11.1990 US 19900614616 (71) Applicant: THE BOARD OF TRUSTEES OF THE LELAND STANFORD JUNIOR UNIVERSITY Stanford, CA 94305-6225 (US)	(72) Inventors: BUTCHER, Eugene, C. Portola Valley, CA 94025 (US) PICKER, Louis Dallas, TX 75230 (US) BERG, Ellen, Lakey Fremont, Ca 94536 (US) (74) Representative: Glawe, Delfs, Moll & Partner  Patentanwälte Postfach 26 01 62 D-80058 München D-80058 München (DE)