(19)
(11) EP 0 559 755 A1

(12)

(43) Date of publication:
15.09.1993 Bulletin 1993/37

(21) Application number: 92900730.0

(22) Date of filing: 12.11.1991
(51) International Patent Classification (IPC): 
A61K 31/ 415( . )
A61K 31/ 42( . )
A61K 31/ 675( . )
A61P 9/ 12( . )
A61P 15/ 00( . )
A61P 27/ 06( . )
C07D 233/ 54( . )
C07D 233/ 68( . )
C07D 233/ 72( . )
C07D 233/ 78( . )
C07D 233/ 90( . )
C07D 403/ 04( . )
C07D 403/ 12( . )
C07D 405/ 06( . )
C07D 405/ 14( . )
C07D 409/ 12( . )
C07D 413/ 06( . )
C07D 413/ 14( . )
C07D 417/ 12( . )
A61K 31/ 4166( . )
A61K 31/ 425( . )
A61P 9/ 00( . )
A61P 13/ 02( . )
A61P 27/ 02( . )
A61P 43/ 00( . )
C07D 233/ 64( . )
C07D 233/ 70( . )
C07D 233/ 76( . )
C07D 233/ 88( . )
C07D 233/ 92( . )
C07D 403/ 06( . )
C07D 403/ 14( . )
C07D 405/ 12( . )
C07D 409/ 06( . )
C07D 409/ 14( . )
C07D 413/ 12( . )
C07D 417/ 06( . )
C07D 417/ 14( . )
(86) International application number:
PCT/US1991/008426
(87) International publication number:
WO 1992/009278 (11.06.1992 Gazette 1992/13)
(84) Designated Contracting States:
BE CH DE FR GB IT LI NL

(30) Priority: 30.11.1990 US 19900621188

(71) Applicant: SMITHKLINE BEECHAM CORPORATION
King of Prussia, PA 19406-0939 (US)

(72) Inventors:
  • KEENAN, Richard, McCulloch
    Malvern, PA 19355 (US)
  • MORGAN, Tina
    Audubon, PA 19403 (US)

(74) Representative: Thompson, Clive Beresford 
SmithKline Beecham plc Corporate Intellectual Property SB House Great West Road
Brentford, Middlesex TW8 9BD
Brentford, Middlesex TW8 9BD (GB)

   


(54) SUBSTITUTED 5-ARYL IMIDAZOLES