(19)
(11) EP 0 563 239 A1

(12)

(43) Date of publication:
06.10.1993 Bulletin 1993/40

(21) Application number: 92902630.0

(22) Date of filing: 09.12.1991
(51) International Patent Classification (IPC): 
A61K 35/ 24( . )
A61K 48/ 00( . )
C07K 14/ 715( . )
C12N 7/ 00( . )
C12N 15/ 867( . )
A61K 35/ 76( . )
A61P 29/ 00( . )
C12N 5/ 10( . )
C12N 15/ 09( . )
A61K 38/ 00( . )
(86) International application number:
PCT/US1991/009231
(87) International publication number:
WO 1992/011359 (09.07.1992 Gazette 1992/17)
(84) Designated Contracting States:
CH DE ES FR GB IT LI NL SE

(30) Priority: 20.12.1990 US 19900630981

(71) Applicant: UNIVERSITY OF PITTSBURGH OF THE COMMONWEALTH SYSTEM OF HIGHER EDUCATION
Pittsburgh, PA 15260 (US)

(72) Inventors:
  • GLORIOSO, Joseph, C.
    Cheswick, PA 15024 (US)
  • EVANS, Christopher, H.
    Pittsburgh, PA 15211 (US)
  • ROBBINS, Paul, D.
    Pittsburgh, PA 15232 (US)
  • BANDARA, Geethani
    Pittsburgh, PA 15232 (US)

(74) Representative: Baillie, Iain Cameron 
c/o Ladas & Parry Altheimer Eck 2
D-80331 München
D-80331 München (DE)

   


(54) A TRUNCATED INTERLEUKIN-1 RECEPTOR GENE FOR THE TREATMENT OF ARTHRITIS