(19)

(11)

EP 0 563 294 A1

(12)

(43) Date of publication: 06.10.1993 Bulletin 1993/40 (21) Application number: 92903625.0 (22) Date of filing: 16.12.1991

(51) International Patent Classification (IPC):  A61K 47/ 00( . ) A61K 47/ 48( . ) (86) International application number: PCT/US1991/009463 (87) International publication number: WO 1992/011038 (09.07.1992 Gazette 1992/17)

(84) Designated Contracting States: AT BE CH DE DK ES FR GB GR IT LI LU NL SE (30) Priority: 21.12.1990 US 19900632290 (71) Applicant: RICHARDSON-VICKS, INC. Shelton, CT 06484 (US)	(72) Inventors: KELLEHER, William Joseph Storrs, CT 06268 (US) CARPANZANO, Anthony, Earl Sherman, CT 06784 (US) (74) Representative: Canonici, Jean-Jacques, et al  Procter & Gamble European Technical Center N.V. Temselaan 100 B-1853 Strombeek-Bever B-1853 Strombeek-Bever (BE)