(19)
(11) EP 0 571 554 A1

(12)

(43) Date of publication:
01.12.1993 Bulletin 1993/48

(21) Application number: 92907699.0

(22) Date of filing: 14.01.1992
(51) International Patent Classification (IPC): 
C07K 14/ 18( . )
C12N 1/ 21( . )
C12N 15/ 40( . )
A61K 39/ 00( . )
C07K 16/ 10( . )
C12N 15/ 113( . )
C12P 21/ 08( . )
(86) International application number:
PCT/US1992/000356
(87) International publication number:
WO 1992/012992 (06.08.1992 Gazette 1992/21)
(84) Designated Contracting States:
AT BE CH DE DK ES FR GB GR IT LI LU MC NL SE

(30) Priority: 14.01.1991 US 19910639809

(71) Applicant: JAMES N. GAMBLE INSTITUTE OF MEDICAL RESEARCH
Cincinnati, OH 45219 (US)

(72) Inventors:
  • KOTWAL, Girish, J.
    Cincinnati, OH 45231 (US)
  • BAROUDY, Bahige, M.
    Cincinnati, OH 45236 (US)

(74) Representative: Allen, Oliver John Richard 
Lloyd Wise, Tregear & Co. Norman House 105-109 Strand
London, WC2R 0AE
London, WC2R 0AE (GB)

   


(54) BASIC STRUCTURAL IMMUNOGENIC POLYPEPTIDES HAVING EPITOPES FOR HCV, ANTIBODIES, POLYNUCLEOTIDE SEQUENCES, VACCINES AND METHODS