NUCLEIC ACID ENCODING INSULIN RECEPTOR SUBSTRATE-1 (IRS-1), IRS-1 PROTEIN, DISEASES, THERAPY ASSOCIATED WITH THE METABOLISM OF IRS-1 - Patent 0572508

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EP 0 572 508 A1

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(43)	Date of publication:
	08.12.1993 Bulletin 1993/49

(21)	Application number: 92906151.0

(22)	Date of filing: 17.01.1992

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International Patent Classification (IPC):

C07K 14/ 47^{( . )}
C12Q 1/ 68^{( . )}

C07K 16/ 18^{( . )}
A61K 38/ 00^{( . )}

(86)	International application number:
	PCT/US1992/000437

(87)	International publication number:
	WO 1992/013083 (06.08.1992 Gazette 1992/21)

(84)	Designated Contracting States:
	CH DE DK LI

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Priority:

18.01.1991 US 19910643982

(71)	Applicant: THE JOSLIN DIABETES CENTER, INC.
	Boston, MA 02215 (US)

(72)	Inventors:
	KAHN, C., Ronald West Newton, MA 02165 (US) WHITE, Morris, F. West Roxbury, MA 02131 (US) ROTHENBERG, Paul, Louis Narberth, PA 19072 (US)

(74)	Representative: Deans, Michael John Percy
	Lloyd Wise, Tregear & CO. Norman House 105-109 Strand London WC2R OAE London WC2R OAE (GB)

(54)	NUCLEIC ACID ENCODING INSULIN RECEPTOR SUBSTRATE-1 (IRS-1), IRS-1 PROTEIN, DISEASES, THERAPY ASSOCIATED WITH THE METABOLISM OF IRS-1