(19)
(11) EP 0 573 540 A1

(12)

(43) Date of publication:
15.12.1993 Bulletin 1993/50

(21) Application number: 92906574.0

(22) Date of filing: 02.03.1992
(51) International Patent Classification (IPC): 
A61K 38/ 23( . )
C07K 1/ 22( . )
C07K 14/ 585( . )
C12P 21/ 02( . )
C07K 1/ 113( . )
C07K 14/ 575( . )
C12N 9/ 02( . )
(86) International application number:
PCT/DK1992/000064
(87) International publication number:
WO 1992/015695 (17.09.1992 Gazette 1992/24)
(84) Designated Contracting States:
AT BE CH DE DK ES FR GB GR IT LI LU MC NL SE

(30) Priority: 01.03.1991 DK 19910000373
15.04.1991 DK 19910000676

(71) Applicant: CARLBIOTECH LTD. A/S
DK-2200 Copenhagen N (DK)

(72) Inventors:
  • AASMUL-OLSEN, Stig
    DK-2942 Skodsborg (DK)
  • CHRISTENSEN, Kurt Asbaek
    DK-4700 Naestved (DK)
  • WIDMER, Fred
    Ryde, NSW 2112 (AU)

(74) Representative: Christiansen, Ejvind, et al 
HOFMAN-BANG & BOUTARD A/S Adelgade 15
DK-1304 Copenhagen K
DK-1304 Copenhagen K (DK)

   


(54) PROCESS FOR THE C-TERMINAL MODIFICATION OF PEPTIDES HAVING A C-TERMINAL PENULTIMATE PROLINE RESIDUE