6,9 BIS(SUBSTITUTED-AMINO)BENZO g]ISOQUINOLINE-5,10-DIONES - Patent 0575526

(19)

(11)

EP 0 575 526 A1

(12)

(43)	Date of publication:
	29.12.1993 Bulletin 1993/52

(21)	Application number: 92908816.0

(22)	Date of filing: 09.03.1992

(51)

International Patent Classification (IPC):

A61K 31/ 435^{( . )}
A61K 31/ 535^{( . )}
C07D 221/ 06^{( . )}
C07D 401/ 14^{( . )}

A61K 31/ 473^{( . )}
A61P 35/ 00^{( . )}
C07D 221/ 08^{( . )}

(86)	International application number:
	PCT/US1992/001606

(87)	International publication number:
	WO 1992/015300 (17.09.1992 Gazette 1992/24)

(84)	Designated Contracting States:
	AT BE CH DE DK ES FR GB GR IT LI LU NL SE

(30)

Priority:

08.03.1991 US 19910665954
29.01.1992 US 19920827302

(71)	Applicant: THE UNIVERSITY OF VERMONT
	Burlington, Vermont 05405-0160 (US)

(72)	Inventor:
	KRAPCHO, A., Paul Shelburne, VT 05482 (US)

(74)	Representative: Weber, Manfred, Dr.
	c/o Boehringer Mannheim GmbH, Patentabteilung, Sandhoferstrasse 116 D-68298 Mannheim D-68298 Mannheim (DE)

(54)	6,9 BIS(SUBSTITUTED-AMINO)BENZO g]ISOQUINOLINE-5,10-DIONES