(19)
(11)
EP 0 575 537 A1
(12)
(43)
Date of publication:
29.12.1993
Bulletin 1993/52
(21)
Application number:
92909064.0
(22)
Date of filing:
09.03.1992
(51)
International Patent Classification (IPC):
A61K
38/
00
( . )
C07K
14/
00
( . )
C12N
5/
10
( . )
C12P
21/
02
( . )
A61P
37/
00
( . )
C07K
14/
705
( . )
C12N
15/
09
( . )
(86)
International application number:
PCT/US1992/001867
(87)
International publication number:
WO 1992/015671
(
17.09.1992
Gazette 1992/24)
(84)
Designated Contracting States:
AT BE CH DE DK ES FR GB GR IT LI LU MC NL SE
(30)
Priority:
08.03.1991
US 19910666809
(71)
Applicant:
CYTOMED, INC.
Cambridge, MA 02139 (US)
(72)
Inventors:
KO, Jone, Long
Cambridge, MA 02138 (US)
IP, Stephen, H.
Sudbury, MA 01776 (US)
(74)
Representative:
Bassett, Richard Simon, et al
ERIC POTTER & CLARKSON St. Mary's Court St. Mary's Gate
Nottingham NG1 1LE
Nottingham NG1 1LE (GB)
(54)
SOLUBLE CD28 PROTEINS AND METHODS OF TREATMENT THEREWITH