(19)
(11) EP 0 575 557 A1

(12)

(43) Date of publication:
29.12.1993 Bulletin 1993/52

(21) Application number: 92910663.0

(22) Date of filing: 09.03.1992
(51) International Patent Classification (IPC): 
A61K 31/ 70( . )
A61K 31/ 78( . )
A61P 7/ 02( . )
A61P 9/ 10( . )
A61P 35/ 00( . )
C07K 14/ 705( . )
C12M 1/ 00( . )
A61K 38/ 00( . )
A61K 31/ 702( . )
A61K 38/ 16( . )
A61P 9/ 00( . )
A61P 29/ 00( . )
C07H 3/ 06( . )
C07K 16/ 28( . )
C12N 5/ 06( . )
(86) International application number:
PCT/US1992/001915
(87) International publication number:
WO 1992/016612 (01.10.1992 Gazette 1992/25)
(84) Designated Contracting States:
AT BE CH DE DK ES FR GB GR IT LI LU MC NL SE

(30) Priority: 11.03.1991 US 19910667453

(71) Applicant: NEW ENGLAND MEDICAL CENTER
Boston, MA 02111 (US)

(72) Inventors:
  • FURIE, Bruce
    Wellesley, MA 02181 (US)
  • FURIE, Barbara, C.
    Welleslay, MA 02181 (US)
  • LARSEN, Eric
    Lebanon, NH 03766 (US)
  • PALABRICA, Theresa
    Quincy, MA 02171 (US)
  • SAJER, Susan
    Brookline, MA 02146 (US)
  • GILBERT, Gary, E.
    Melrose, MA 02181 (US)
  • WAGNER, Denisa, D.
    Wellesley, MA 02181 (US)
  • CELI, Alessandro
    54100 Massa (MS) (IT)
  • ERBAN, John
    Wakefield, MA 01880 (US)
  • GIBSON, Rosemary
    Boston, Massachusetts 02116 (US)

(74) Representative: Harvey, David Gareth 
Graham Watt & Co. Riverhead
Sevenoaks Kent TN13 2BN
Sevenoaks Kent TN13 2BN (GB)

   


(54) METHOD OF INHIBITING PADGEM-MEDIATED INTERACTIONS USING AN INHIBITOR COMPRISING A 2,6 SIALIC ACID COMPONENT