(19)
(11) EP 0 575 583 A1

(12)

(43) Date of publication:
29.12.1993 Bulletin 1993/52

(21) Application number: 93901383.0

(22) Date of filing: 10.12.1992
(51) International Patent Classification (IPC): 
A61K 51/ 04( . )
C07B 59/ 00( . )
C07D 487/ 08( . )
A61K 51/ 10( . )
C07D 471/ 08( . )
(86) International application number:
PCT/US1992/010663
(87) International publication number:
WO 1993/012112 (24.06.1993 Gazette 1993/15)
(84) Designated Contracting States:
AT BE CH DE DK ES FR GB GR IE IT LI LU MC NL PT SE

(30) Priority: 10.12.1991 US 19910805392

(71) Applicant: THE DOW CHEMICAL COMPANY
Midland, Michigan 48640 (US)

(72) Inventors:
  • KIEFER, Garry, E.
    Lake Jackson, TX 77566 (US)
  • SIMON, Jaime
    Angleton, TX 77515 (US)

(74) Representative: Burford, Anthony Frederick 
W.H. Beck, Greener & Co. 7 Stone Buildings Lincoln's Inn
London WC2A 3SZ
London WC2A 3SZ (GB)

   


(54) BICYCLOPOLYAZAMACROCYCLOCARBOXYLIC ACID COMPLEXES, THEIR CONJUGATES PROCESSES FOR THEIR PREPARATION, AND USE AS RADIOPHARMACEUTICALS