(19)
(11)
EP 0 577 725 A1
(12)
(43)
Date of publication:
12.01.1994
Bulletin 1994/02
(21)
Application number:
92909373.0
(22)
Date of filing:
27.03.1992
(51)
International Patent Classification (IPC):
A61K
31/
66
( . )
A61K
31/
70
( . )
A61K
31/
7034
( . )
A61K
31/
7042
( . )
A61K
31/
7064
( . )
A61K
31/
7072
( . )
A61K
31/
708
( . )
A61P
43/
00
( . )
C07F
9/
165
( . )
C07F
9/
572
( . )
C07F
9/
59
( . )
C07F
9/
6506
( . )
C07F
9/
6512
( . )
C07F
9/
6558
( . )
C07H
15/
252
( . )
C07H
19/
10
( . )
C07J
51/
00
( . )
C07J
71/
00
( . )
A61K
31/
675
( . )
A61K
31/
7028
( . )
A61K
31/
704
( . )
A61K
31/
7052
( . )
A61K
31/
7068
( . )
A61K
31/
7076
( . )
A61K
47/
48
( . )
C07F
9/
09
( . )
C07F
9/
553
( . )
C07F
9/
576
( . )
C07F
9/
645
( . )
C07F
9/
6509
( . )
C07F
9/
6547
( . )
C07F
9/
6561
( . )
C07H
19/
04
( . )
C07H
19/
20
( . )
C07J
63/
00
( . )
(86)
International application number:
PCT/US1992/002239
(87)
International publication number:
WO 1992/017185
(
15.10.1992
Gazette 1992/26)
(84)
Designated Contracting States:
AT BE CH DE DK ES FR GB GR IT LI LU MC NL SE
(30)
Priority:
29.03.1991
US 19910677304
(71)
Applicant:
UNIVERSITY OF FLORIDA
Gainesville, Florida 32611 (US)
(72)
Inventor:
BODOR, Nicholas S.
Gainesville, FL 32608 (US)
(74)
Representative:
Pendlebury, Anthony, et al
PAGE, WHITE & FARRER 54 Doughty Street
London WC1N 2LS
London WC1N 2LS (GB)
(54)
TARGETED DRUG DELIVERY VIA MIXED PHOSPHATE DERIVATIVES