(19)
(11) EP 0 579 731 A1

(12)

(43) Date of publication:
26.01.1994 Bulletin 1994/04

(21) Application number: 92910006.0

(22) Date of filing: 04.04.1992
(51) International Patent Classification (IPC): 
A61K 31/ 165( . )
A61K 31/ 235( . )
A61P 11/ 00( . )
A61P 29/ 00( . )
A61P 43/ 00( . )
C07C 65/ 105( . )
C07C 65/ 24( . )
C07C 69/ 773( . )
C07C 69/ 92( . )
C07C 317/ 44( . )
C07C 323/ 62( . )
A61K 31/ 19( . )
A61P 9/ 00( . )
A61P 17/ 00( . )
A61P 37/ 08( . )
C07C 65/ 01( . )
C07C 65/ 11( . )
C07C 69/ 76( . )
C07C 69/ 78( . )
C07C 235/ 66( . )
C07C 317/ 46( . )
(86) International application number:
PCT/US1992/002742
(87) International publication number:
WO 1992/017172 (15.10.1992 Gazette 1992/26)
(84) Designated Contracting States:
BE CH DE FR GB IT LI NL

(30) Priority: 05.04.1991 US 19910682157

(71) Applicant: SMITHKLINE BEECHAM CORPORATION
King of Prussia, PA 19406-0939 (US)

(72) Inventors:
  • DAINES, Robert A.
    Lansdale, PA 19446 (US)
  • KINGSBURY, William D.
    Wayne, PA 19087 (US)

(74) Representative: Giddings, Peter John, Dr. 
SmithKline Beecham plc Corporate Intellectual Property SB House Great West Road
Brentford, Middlesex TW8 9BD
Brentford, Middlesex TW8 9BD (GB)

   


(54) DISUBSTITUTED NAPHTHALENES