(19)
(11) EP 0 581 923 A1

(12)

(43) Date of publication:
09.02.1994 Bulletin 1994/06

(21) Application number: 93902386.0

(22) Date of filing: 15.01.1993
(51) International Patent Classification (IPC): 
A61K 31/ 66( . )
C07F 9/ 38( . )
C07F 9/ 6533( . )
A61P 43/ 00( . )
C07F 9/ 40( . )
(86) International application number:
PCT/GB1993/000086
(87) International publication number:
WO 1993/014096 (22.07.1993 Gazette 1993/18)
(84) Designated Contracting States:
AT BE CH DE DK ES FR GB GR IE IT LI LU MC NL PT SE

(30) Priority: 15.01.1992 GB 19920000826

(71) Applicant: CELLTECH LIMITED
Slough Berkshire SL1 4EN (GB)

(72) Inventors:
  • BEELEY, Nigel, Robert, Arnold
    Thame Oxfordshire OX9 3LQ (GB)
  • MILLICAN, Thomas, Andrew
    Maidenhead Berkshire SL6 0DY (GB)
  • MORPHY, John, Richard
    Maidenhead Berkshire SL6 1YY (GB)

(74) Representative: Hallybone, Huw George, et al 
CARPMAELS AND RANSFORD 43 Bloomsbury Square
London WC1A 2RA
London WC1A 2RA (GB)

   


(54) PHOSPHONO DERIVATIVES OF AMINO ACIDS AS METALLOPROTEINASE INHIBITORS