2-(PYRROLIDINYL-1-METHYL)-PIPERIDINE DERIVATIVES AND THEIR USE AS KAPPA-RECEPT OR AGONISTS - Patent 0585296

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EP 0 585 296 A1

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(43)	Date of publication:
	09.03.1994 Bulletin 1994/10

(21)	Application number: 92910424.0

(22)	Date of filing: 15.05.1992

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International Patent Classification (IPC):

A61K 31/ 445^{( . )}
A61P 7/ 10^{( . )}
A61P 9/ 10^{( . )}
A61P 25/ 02^{( . )}
A61P 25/ 28^{( . )}
C07D 401/ 06^{( . )}

A61K 31/ 4427^{( . )}
A61P 9/ 06^{( . )}
A61P 11/ 00^{( . )}
A61P 25/ 08^{( . )}
A61P 29/ 00^{( . )}

(86)	International application number:
	PCT/EP1992/001111

(87)	International publication number:
	WO 1992/020657 (26.11.1992 Gazette 1992/29)

(84)	Designated Contracting States:
	BE CH DE FR GB IT LI NL

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Priority:

21.05.1991 GB 19910010951
09.07.1991 GB 19910014772

(71)	Applicant: SMITHKLINE BEECHAM FARMACEUTICI S.p.A.
	I-20021 Baranzate di Bollate (MI) (IT)

(72)	Inventors:
	GIARDINA, Giuseppe I-20021 Baranzate (IT) COLLE, Roberto I-20021 Baranzate (IT) CLARKE, Geoffrey Douglas I-20021 Baranzate (IT)

(74)	Representative: Russell, Brian John
	SmithKline Beecham plc Corporate Intellectual Property SB House Great West Road Brentford, Middlesex TW8 9BD Brentford, Middlesex TW8 9BD (GB)

(54)	2-(PYRROLIDINYL-1-METHYL)-PIPERIDINE DERIVATIVES AND THEIR USE AS KAPPA-RECEPT OR AGONISTS