TREATMENT OF COLORECTAL CARCINOMA WITH ANTISENSE OLIGONUCLEOTIDES TO C-MYB PROTO-ONCOGENE - Patent 0585399

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EP 0 585 399 A1

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(43)	Date of publication:
	09.03.1994 Bulletin 1994/10

(21)	Application number: 92913962.0

(22)	Date of filing: 22.05.1992

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International Patent Classification (IPC):

A61K 31/ 70^{( . )}
C07H 21/ 04^{( . )}
C12N 15/ 09^{( . )}
A61K 38/ 00^{( . )}

A61P 35/ 00^{( . )}
C07K 14/ 82^{( . )}
C12N 15/ 113^{( . )}

(86)	International application number:
	PCT/US1992/004318

(87)	International publication number:
	WO 1992/020348 (26.11.1992 Gazette 1992/29)

(84)	Designated Contracting States:
	AT BE CH DE DK ES FR GB GR IT LI LU MC NL SE

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Priority:

23.05.1991 US 19910704862

(71)	Applicant: Temple University of the Commonwealth System of Higher Education
	Philadelphia PA 19122 (US)

(72)	Inventors:
	CALABRETTA, Bruno Philadelphia, PA 19103 (US) GEWIRTZ, Alan, M. Philadelphia, PA 19130 (US)

(74)	Representative: W.P. THOMPSON & CO.
	Eastcheap House Central Approach Letchworth, Hertfordshire SG6 3DS Letchworth, Hertfordshire SG6 3DS (GB)

(54)	TREATMENT OF COLORECTAL CARCINOMA WITH ANTISENSE OLIGONUCLEOTIDES TO C-MYB PROTO-ONCOGENE