(19)
(11) EP 0 586 466 A1

(12)

(43) Date of publication:
16.03.1994 Bulletin 1994/11

(21) Application number: 92910914.0

(22) Date of filing: 30.04.1992
(51) International Patent Classification (IPC): 
A61K 31/ 415( . )
A61K 31/ 4184( . )
A61P 9/ 12( . )
C07D 235/ 02( . )
C07D 235/ 08( . )
C07D 403/ 10( . )
 A61K 31/ 41( . )
A61P 9/ 00( . )
A61P 43/ 00( . )
C07D 235/ 06( . )
C07D 235/ 10( . )
(86) International application number:
PCT/US1992/003440
(87) International publication number:
WO 1992/019211 (12.11.1992 Gazette 1992/28)
(84) Designated Contracting States:
AT BE CH DE DK ES FR GB GR IT LI LU MC NL SE

(30) Priority: 08.05.1991 JP 19910102639
12.06.1991 JP 19910140057
16.08.1991 JP 19910205879
27.12.1991 JP 19910346283

(71) Applicant: THE UPJOHN COMPANY
Kalamazoo, Michigan 49001 (US)

(72) Inventors:
  • KOH, Keiko
    Tsukuba-shi, Ibaraki 305 (JP)
  • ITOH, Noriie
    Inashiki-gun, Ibaraki 300-03 (JP)
  • OZAWA, Kazunori
    Tsukuba-shi, Ibaraki 305 (JP)
  • KUSHIDA, Hiroshi
    Shimodate-shi, Ibaraki 308 (JP)
  • MCWHORTER, William, W., Jr.
    Kalamazoo, MI 49004 (US)

(74) Representative: Perry, Robert Edward 
GILL JENNINGS & EVERY Broadgate House 7 Eldon Street
London EC2M 7LH
London EC2M 7LH (GB)

   


(54) IMIDAZOBENZOQUINONES AND COMPOSITION FOR PREVENTING OR TREATING HYPERTENSION OR CONGESTIVE HEART FAILURE CONTAINING THE SAME