(19)
(11) EP 0 586 553 A1

(12)

(43) Date of publication:
16.03.1994 Bulletin 1994/11

(21) Application number: 92912819.0

(22) Date of filing: 11.03.1992
(51) International Patent Classification (IPC): 
A61K 31/ 40( . )
A61K 31/ 47( . )
A61P 25/ 00( . )
C07D 209/ 60( . )
C07D 221/ 08( . )
A61K 31/ 403( . )
A61K 31/ 473( . )
A61P 25/ 18( . )
C07D 209/ 62( . )
C07D 227/ 06( . )
(86) International application number:
PCT/US1992/001652
(87) International publication number:
WO 1992/021654 (10.12.1992 Gazette 1992/31)
(84) Designated Contracting States:
AT BE CH DE DK ES FR GB GR IT LI LU MC NL SE

(30) Priority: 20.05.1991 US 19910702813

(71) Applicant: THE UPJOHN COMPANY
Kalamazoo, Michigan 49001 (US)

(72) Inventors:
  • LIN, Chiu-Hong
    Portage, MI 49002 (US)
  • PIERCEY, Montford, E.
    Kalamazoo, MI 49008 (US)
  • HAADSMA-SVENSSON, Susanne, R.
    S-411 25 Göteborg (SE)

(74) Representative: Perry, Robert Edward 
GILL JENNINGS & EVERY Broadgate House 7 Eldon Street
London EC2M 7LH
London EC2M 7LH (GB)

   


(54) CARBOXAMIDO-(3,2N)-CARBOCYCLIC-2-AMINOTETRALIN DERIVATIVES