REFOLDING AND PURIFICATION OF INSULIN-LIKE GROWTH FACTOR I - Patent 0586667

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EP 0 586 667 A1

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(43)	Date of publication:
	16.03.1994 Bulletin 1994/11

(21)	Application number: 93907573.0

(22)	Date of filing: 19.03.1993

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International Patent Classification (IPC):

C07K 1/ 113^{( . )}
C12N 9/ 48^{( . )}
A61K 38/ 00^{( . )}

C07K 14/ 65^{( . )}
C12N 15/ 18^{( . )}

(86)	International application number:
	PCT/US1993/002457

(87)	International publication number:
	WO 1993/019084 (30.09.1993 Gazette 1993/24)

(84)	Designated Contracting States:
	AT BE CH DE DK ES FR GB GR IE IT LI LU MC NL PT SE

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Priority:

24.03.1992 US 19920858161

(71)	Applicant: SYNERGEN, INC.
	Boulder Colorado 80301 (US)

(72)	Inventors:
	COX, George, N. Louisville, CO 80027 (US) MCDERMOTT, Martin, J. Boulder, CO 80302 (US) GLEASON, Tom, M. Boulder, CO 80303 (US)

(74)	Representative: Grünecker, Kinkeldey, Stockmair & Schwanhäusser Anwaltssozietät
	Maximilianstrasse 58 D-80538 München D-80538 München (DE)

(54)	REFOLDING AND PURIFICATION OF INSULIN-LIKE GROWTH FACTOR I