(19)
(11) EP 0 587 765 A1

(12)

(43) Date of publication:
23.03.1994 Bulletin 1994/12

(21) Application number: 92913474.0

(22) Date of filing: 01.06.1992
(51) International Patent Classification (IPC): 
C07K 14/ 33( . )
C12P 21/ 08( . )
C12N 15/ 31( . )
A61K 39/ 00( . )
(86) International application number:
PCT/US1992/005023
(87) International publication number:
WO 1992/021374 (10.12.1992 Gazette 1992/31)
(84) Designated Contracting States:
AT BE CH DE DK ES FR GB GR IT LI LU MC NL SE

(30) Priority: 06.06.1991 US 19910711084

(71) Applicant: MEDIMMUNE, INC.
Gaithersburg, MD 20878 (US)

(72) Inventors:
  • STOVER, Charles, K.
    Silver Spring, MD (US)
  • DELA CRUZ, Vidal
    Rockville, MD (US)

(74) Representative: Segeth, Wolfgang 
Patentanwälte Louis, Pöhlau, Lohrentz & Segeth Postfach 30 55
D-90014 Nürnberg
D-90014 Nürnberg (DE)

   


(54) INDUCTION OF IMMUNE RESPONSE AGAINST TETANUS TOXIN THROUGH ADMINISTRATION OF MYCOBACTERIA EXPRESSING TETANUS TOXIN OR FRAGMENTS